Long-term and stable correction of uremic anemia by intramuscular injection of plasmids containing hypoxia-regulated system of erythropoietin expression

Relative deficiency in production of glycoprotein hormone erythropoietin (Epo) is a major cause of renal anemia. This study planned to investigate whether the hypoxia-regulated system of Epo expression, constructed by fusing Epo gene to the chimeric phosphoglycerate kinase (PGK) hypoxia response ele...

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Bibliographic Details
Main Authors: Sun, Jifeng, Wang, Yarong, Yang, Jie, Du, Dewei, Li, Zhanting, Wei, Junxia, Yang, Angang
Format: Online
Language:English
Published: Korean Society for Biochemistry and Molecular Biology 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509184/