ATF6α/β-mediated adjustment of ER chaperone levels is essential for development of the notochord in medaka fish

ATF6α/β-mediated adjustment of ER chaperone levels is essential for development of the notochord in medaka fish

The endoplasmic reticulum (ER) membrane-bound transcription factors ATF6α and ATF6β mediate adjustment of chaperone levels to increased demands in the ER, which is essential for development of the notochord; the latter synthesizes and secretes large amounts of extracellular matrix proteins to serve...

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Bibliographic Details
Main Authors: Ishikawa, Tokiro, Okada, Tetsuya, Ishikawa-Fujiwara, Tomoko, Todo, Takeshi, Kamei, Yasuhiro, Shigenobu, Shuji, Tanaka, Minoru, Saito, Taro L., Yoshimura, Jun, Morishita, Shinichi, Toyoda, Atsushi, Sakaki, Yoshiyuki, Taniguchi, Yoshihito, Takeda, Shunichi, Mori, Kazutoshi
Format: Online
Language:English
Published: The American Society for Cell Biology 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639050/

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