ATF6α/β-mediated adjustment of ER chaperone levels is essential for development of the notochord in medaka fish
The endoplasmic reticulum (ER) membrane-bound transcription factors ATF6α and ATF6β mediate adjustment of chaperone levels to increased demands in the ER, which is essential for development of the notochord; the latter synthesizes and secretes large amounts of extracellular matrix proteins to serve...
Main Authors: | , , , , , , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
The American Society for Cell Biology
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639050/ |