Collagen II Is Essential for the Removal of the Notochord and the Formation of Intervertebral Discs

Collagen II is a fibril-forming collagen that is mainly expressed in cartilage. Collagen II–deficient mice produce structurally abnormal cartilage that lacks growth plates in long bones, and as a result these mice develop a skeleton without endochondral bone formation. Here, we report that Col2a1-nu...

Full description

Bibliographic Details
Main Authors: Aszódi, Attila, Chan, Danny, Hunziker, Ernst, Bateman, John F., Fässler, Reinhard
Format: Online
Language:English
Published: The Rockefeller University Press 1998
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133086/