mTOR-Controlled Autophagy Requires Intracellular Ca2+ Signaling

mTOR-Controlled Autophagy Requires Intracellular Ca2+ Signaling

Autophagy is a lysosomal degradation pathway important for cellular homeostasis and survival. Inhibition of the mammalian target of rapamycin (mTOR) is the best known trigger for autophagy stimulation. In addition, intracellular Ca2+ regulates autophagy, but its exact role remains ambiguous. Here, w...

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Bibliographic Details
Main Authors: Decuypere, Jean-Paul, Kindt, Dimphny, Luyten, Tomas, Welkenhuyzen, Kirsten, Missiaen, Ludwig, De Smedt, Humbert, Bultynck, Geert, Parys, Jan B.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614970/

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