All PI3Kinase signaling is not mTOR: dissecting mTOR-dependent and independent signaling pathways in T cells

The mechanistic target of rapamycin (mTOR) is emerging as playing a central role in regulating T cell activation, differentiation, and function. mTOR integrates diverse signals from the immune microenvironment to shape the outcome of T cell receptor (TCR) antigen recognition. Phosphatidylinositol 3-...

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Bibliographic Details
Main Authors: Gamper, Christopher J., Powell, Jonathan D.
Format: Online
Language:English
Published: Frontiers Media S.A. 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466461/