STIM1 as a key regulator for Ca2+ homeostasis in skeletal-muscle development and function

Stromal interaction molecules (STIM) were identified as the endoplasmic-reticulum (ER) Ca2+ sensor controlling store-operated Ca2+ entry (SOCE) and Ca2+-release-activated Ca2+ (CRAC) channels in non-excitable cells. STIM proteins target Orai1-3, tetrameric Ca2+-permeable channels in the plasma membr...

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Bibliographic Details
Main Authors: Kiviluoto, Santeri, Decuypere, Jean-Paul, De Smedt, Humbert, Missiaen, Ludwig, Parys, Jan B, Bultynck, Geert
Format: Online
Language:English
Published: BioMed Central 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156639/