Positional Mapping and Candidate Gene Analysis of the Mouse Ccs3 Locus That Regulates Differential Susceptibility to Carcinogen-Induced Colorectal Cancer

Positional Mapping and Candidate Gene Analysis of the Mouse Ccs3 Locus That Regulates Differential Susceptibility to Carcinogen-Induced Colorectal Cancer

The Ccs3 locus on mouse chromosome 3 regulates differential susceptibility of A/J (A, susceptible) and C57BL/6J (B6, resistant) mouse strains to chemically-induced colorectal cancer (CRC). Here, we report the high-resolution positional mapping of the gene underlying the Ccs3 effect. Using phenotype/...

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Bibliographic Details
Main Authors: Meunier, Charles, Van Der Kraak, Lauren, Turbide, Claire, Groulx, Normand, Labouba, Ingrid, Cingolani, Pablo, Blanchette, Mathieu, Yeretssian, Garabet, Mes-Masson, Anne-Marie, Saleh, Maya, Beauchemin, Nicole, Gros, Philippe
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597735/

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