A Two-Locus System Controls Susceptibility to Colitis-Associated Colon Cancer in Mice

We have previously shown that the differential susceptibility of A/J (susceptible) and C57BL/6J (B6, resistant) mouse strains to azoxymethane (AOM)-induced colorectal cancer (CRC) is controlled by the chromosome 3 locus, Ccs3. We report that A/J and B6 mice also show differential susceptibility to c...

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Bibliographic Details
Main Authors: Van Der Kraak, Lauren, Meunier, Charles, Turbide, Claire, Jothy, Serge, Gaboury, Louis, Marcus, Victoria, Chang, Sing Yun, Beauchemin, Nicole, Gros, Philippe
Format: Online
Language:English
Published: Impact Journals LLC 2010
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248117/