Differential Activity of Type I Interferon Subtypes for Dendritic Cell Differentiation

The type I interferon (IFN) family comprises 15 cytokines (in human 13α, 1β, 1ω), which exert several cellular functions through binding to a common receptor. Despite initial activation of the same Jak/Stat signalling pathway, the cellular response may differ depending on type I IFN subtype. We inve...

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Bibliographic Details
Main Authors: Garcin, Geneviève, Bordat, Yann, Chuchana, Paul, Monneron, Danièle, Law, Helen K. W., Piehler, Jacob, Uzé, Gilles
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589429/