Role of Epigenetics in Chronic Myeloid Leukemia
The efficacy of therapeutic modalities in chronic myeloid leukemia (CML) depends on both genetic and epigenetic mechanisms. This review focuses on epigenetic mechanisms involved in the pathogenesis of CML and in resistance of tumor cells to tyrosine kinase inhibitors leading to the leukemic clone es...
Main Authors: | , , |
---|---|
Format: | Online |
Language: | English |
Published: |
Current Science Inc.
2013
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578734/ |