Quantitative Analysis of Mutant Subclones in Chronic Myeloid Leukemia: Comparison of Different Methodological Approaches

Quantitative Analysis of Mutant Subclones in Chronic Myeloid Leukemia: Comparison of Different Methodological Approaches

Identification and quantitative monitoring of mutant BCR-ABL1 subclones displaying resistance to tyrosine kinase inhibitors (TKIs) have become important tasks in patients with Ph-positive leukemias. Different technologies have been established for patient screening. Various next-generation sequencin...

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Bibliographic Details
Main Authors: Preuner, Sandra, Barna, Agnes, Frommlet, Florian, Czurda, Stefan, Konstantin, Byrgazov, Alikian, Mary, Machova Polakova, Katerina, Sacha, Tomasz, Richter, Johan, Lion, Thomas, Gabriel, Christian
Format: Online
Language:English
Published: MDPI 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881468/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881468/

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