Estrogen receptor-α is required for the osteogenic response to mechanical loading in a ligand-independent manner involving its activation function 1 but not 2

Estrogen receptor-α is required for the osteogenic response to mechanical loading in a ligand-independent manner involving its activation function 1 but not 2

Estrogen receptor-α (ERα) is crucial for the adaptive response of bone to loading but the role of endogenous estradiol (E2) for this response is unclear. To determine in vivo the ligand dependency and relative roles of different ERα domains for the osteogenic response to mechanical loading, gene-tar...

Full description

Bibliographic Details
Main Authors: Windahl, Sara H, Saxon, Leanne, Börjesson, Anna E, Lagerquist, Marie K, Frenkel, Baruch, Henning, Petra, Lerner, Ulf H, Galea, Gabriel L, Meakin, Lee B, Engdahl, Cecilia, Sjögren, Klara, Antal, Maria C, Krust, Andrée, Chambon, Pierre, Lanyon, Lance E, Price, Joanna S, Ohlsson, Claes
Format: Online
Language:English
Published: Wiley Subscription Services, Inc., A Wiley Company 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575695/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575695/

Similar Items