The gut microbiota regulates bone mass in mice

The gut microbiota modulates host metabolism and development of immune status. Here we show that the gut microbiota is also a major regulator of bone mass in mice. Germ-free (GF) mice exhibit increased bone mass associated with reduced number of osteoclasts per bone surface compared with conventiona...

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Bibliographic Details
Main Authors: Sjögren, Klara, Engdahl, Cecilia, Henning, Petra, Lerner, Ulf H, Tremaroli, Valentina, Lagerquist, Marie K, Bäckhed, Fredrik, Ohlsson, Claes
Format: Online
Language:English
Published: Wiley Subscription Services, Inc., A Wiley Company 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415623/