Environmental effects on protection against Mycobacterium tuberculosis after immunization with Ad85A
► The environment alters the immune response to an intradermal (i.d.) TB subunit vaccine, Ad85A. ► Ad85A i.d. induces a lung immune response but is less protective against Mtb than intranasal Ad85A. ► Oral administration of environmental mycobacteria reduces Ad85A i.d induced protection. ► In vivo d...
Main Authors: | , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Elsevier Science
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566543/ |