Immunization with different formulations of Mycobacterium tuberculosis antigen 85A induces immune responses with different specificity and protective efficacy☆
•Immunization intranasally with Mtb antigen 85A is more protective than parenterally.•Three 85A vaccines platforms induce responses with differing epitope specificity.•Responses to the CD8 85A70–78 but not the CD8 85A145–152 epitope are protective.
| Main Authors: | , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Elsevier Science
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898716/ |