High-throughput microbial population genomics using the Cortex variation assembler

Summary: We have developed a software package, Cortex, designed for the analysis of genetic variation by de novo assembly of multiple samples. This allows direct comparison of samples without using a reference genome as intermediate and incorporates discovery and genotyping of single-nucleotide poly...

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Bibliographic Details
Main Authors: Iqbal, Zamin, Turner, Isaac, McVean, Gil
Format: Online
Language:English
Published: Oxford University Press 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546798/