Differential confounding of rare and common variants in spatially structured populations
Well-powered genome-wide association studies, now possible through advances in technology and large-scale collaborative projects, promise to reveal the contribution of rare variants to complex traits and disease. However, while population structure is a known confounder of association studies, it is...
Main Authors: | , |
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Format: | Online |
Language: | English |
Published: |
2012
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303124/ |