AffyRNADegradation: control and correction of RNA quality effects in GeneChip expression data
Motivation: Gene expression experiments aim to accurately quantify thousands of transcripts in parallel. Factors posterior to RNA extraction can, however, impair their accurate representation. RNA degradation and differences in the efficiency of amplification affect raw intensity measurements using...
Main Authors: | Fasold, Mario, Binder, Hans |
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Format: | Online |
Language: | English |
Published: |
Oxford University Press
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530908/ |
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