AffyRNADegradation: control and correction of RNA quality effects in GeneChip expression data

Motivation: Gene expression experiments aim to accurately quantify thousands of transcripts in parallel. Factors posterior to RNA extraction can, however, impair their accurate representation. RNA degradation and differences in the efficiency of amplification affect raw intensity measurements using...

Full description

Bibliographic Details
Main Authors: Fasold, Mario, Binder, Hans
Format: Online
Language:English
Published: Oxford University Press 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530908/