Preferred analysis methods for Affymetrix GeneChips revealed by a wholly defined control dataset

A 'spike-in' experiment for Affymetrix GeneChips is described that provides a defined dataset of 3,860 RNA species. A 'best route' combination of analysis methods is presented which allows detection of approximately 70% of true positives before reaching a 10% false discovery rate...

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Bibliographic Details
Main Authors: Choe, Sung E, Boutros, Michael, Michelson, Alan M, Church, George M, Halfon, Marc S
Format: Online
Language:English
Published: BioMed Central 2005
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC551536/