Assessment of T-dependent and T-independent immune responses in cattle using a B cell ELISPOT assay
Understanding the mechanisms that maintain protective antibody levels after immunisation is important for vaccine design. In this study, we have determined the kinetics of plasma and memory B cells detectable in the blood of cattle immunised with model T-dependent or T-independent antigens. Immunisa...
Main Authors: | Grant, Clare FJ, Lefevre, Eric A, Carr, B Veronica, Prentice, Helen, Gubbins, Simon, Pollard, Andrew J, Charreyre, Catherine, Charleston, Bryan |
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Format: | Online |
Language: | English |
Published: |
BioMed Central
2012
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487944/ |
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