Assessment of T-dependent and T-independent immune responses in cattle using a B cell ELISPOT assay

Understanding the mechanisms that maintain protective antibody levels after immunisation is important for vaccine design. In this study, we have determined the kinetics of plasma and memory B cells detectable in the blood of cattle immunised with model T-dependent or T-independent antigens. Immunisa...

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Bibliographic Details
Main Authors: Grant, Clare FJ, Lefevre, Eric A, Carr, B Veronica, Prentice, Helen, Gubbins, Simon, Pollard, Andrew J, Charreyre, Catherine, Charleston, Bryan
Format: Online
Language:English
Published: BioMed Central 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487944/