From compound to target: chemical proteomics and in silico screening identify Hsp90 and CDPK2 as putative targets in Plasmodium falciparum
Main Authors: | Lauciello, Leonardo, Ahmed, Shaheen, Derrer, Bianca, Kappes, Barbara, Wang, Tai, Seebacher, Werner, Scapozza, Leonardo, Perozzo, Remo |
---|---|
Format: | Online |
Language: | English |
Published: |
BioMed Central
2012
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474257/ |
Similar Items
-
Adenosine Kinase of T. b. rhodesiense Identified as the Putative Target of 4-[5-(4-phenoxyphenyl)-2H-pyrazol-3-yl]morpholine Using Chemical Proteomics
by: Kuettel, Sabine, et al.
Published: (2009) -
A Purine Analog Synergizes with Chloroquine (CQ) by Targeting Plasmodium falciparum Hsp90 (PfHsp90)
by: Shahinas, Dea, et al.
Published: (2013) -
Targeting Plasmodium falciparum Hsp90: Towards Reversing Antimalarial Resistance
by: Shahinas, Dea, et al.
Published: (2013) -
Crystal Structures of T. b. rhodesiense Adenosine Kinase Complexed with Inhibitor and Activator: Implications for Catalysis and Hyperactivation
by: Kuettel, Sabine, et al.
Published: (2011) -
Targeting Hsp90 in urothelial carcinoma
by: Chehab, Mahmoud, et al.
Published: (2015)