Adenosine Kinase of T. b. rhodesiense Identified as the Putative Target of 4-[5-(4-phenoxyphenyl)-2H-pyrazol-3-yl]morpholine Using Chemical Proteomics

by Kuettel, Sabine, Mosimann, Marc, Mäser, Pascal, Kaiser, Marcel, Brun, Reto, Scapozza, Leonardo, Perozzo, Remo
Published 2009

Crystal Structures of T. b. rhodesiense Adenosine Kinase Complexed with Inhibitor and Activator: Implications for Catalysis and Hyperactivation

by Kuettel, Sabine, Greenwald, Jason, Kostrewa, Dirk, Ahmed, Shaheen, Scapozza, Leonardo, Perozzo, Remo
Published 2011

From compound to target: chemical proteomics and in silico screening identify Hsp90 and CDPK2 as putative targets in Plasmodium falciparum

by Lauciello, Leonardo, Ahmed, Shaheen, Derrer, Bianca, Kappes, Barbara, Wang, Tai, Seebacher, Werner, Scapozza, Leonardo, Perozzo, Remo
Published 2012

Naphthoquinone Derivatives Exert Their Antitrypanosomal Activity via a Multi-Target Mechanism

by Pieretti, Simone, Haanstra, Jurgen R., Mazet, Muriel, Perozzo, Remo, Bergamini, Christian, Prati, Federica, Fato, Romana, Lenaz, Giorgio, Capranico, Giovanni, Brun, Reto, Bakker, Barbara M., Michels, Paul A. M., Scapozza, Leonardo, Bolognesi, Maria Laura, Cavalli, Andrea
Published 2013