Directional Selection Causes Decanalization in a Group I Ribozyme

A canalized genotype is robust to environmental or genetic perturbations. Canalization is expected to result from stabilizing selection on a well-adapted phenotype. Decanalization, the loss of robustness, might follow periods of directional selection toward a new optimum. The evolutionary forces cau...

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Bibliographic Details
Main Authors: Hayden, Eric J., Weikert, Christian, Wagner, Andreas
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445466/