A ribozyme that triphosphorylates RNA 5′-hydroxyl groups
The RNA world hypothesis describes a stage in the early evolution of life in which RNA served as genome and as the only genome-encoded catalyst. To test whether RNA world organisms could have used cyclic trimetaphosphate as an energy source, we developed an in vitro selection strategy for isolating...
Main Authors: | , |
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Format: | Online |
Language: | English |
Published: |
Oxford University Press
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985629/ |