Mechanisms of covalent self-assembly of the Azoarcus ribozyme from four fragment oligonucleotides
RNA oligomers of length 40–60 nt can self-assemble into covalent versions of the Azoarcus group I intron ribozyme. This process requires a series of recombination reactions in which the internal guide sequence of a nascent catalytic complex makes specific interactions with a complement triplet, CAU,...
| Main Authors: | , , |
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| Format: | Online |
| Language: | English |
| Published: |
Oxford University Press
2008
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2241849/ |