Caged intracellular NMDA receptor blockers for the study of subcellular ion channel function

We have previously synthesized a caged form of the use-dependent N-methyl-D-aspartate (NMDA) receptor ion channel blocker MK801 and used intracellular photolysis of this compound to demonstrate the subcellular location of NMDA receptor ion channels involved in synaptic plasticity. Here, we discuss c...

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Bibliographic Details
Main Authors: Reeve, James E., Kohl, Michael M., Rodríguez-Moreno, Antonio, Paulsen, Ole, Anderson, Harry L.
Format: Online
Language:English
Published: Landes Bioscience 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419105/