Gating of NMDA receptor-mediated hippocampal spike timing-dependent potentiation by mGluR5

Hippocampal long-term potentiation (LTP) is believed to be important for learning and memory. Experimentally, the pairing of precisely timed pre- and postsynaptic spikes within a time window of ∼10 ms can induce timing-dependent LTP (tLTP), but the requirements for induction of tLTP change with deve...

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Bibliographic Details
Main Authors: Kwag, Jeehyun, Paulsen, Ole
Format: Online
Language:English
Published: Pergamon Press 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396853/