Progression of Mouse Skin Carcinogenesis Is Associated with Increased Erα Levels and Is Repressed by a Dominant Negative Form of Erα

Progression of Mouse Skin Carcinogenesis Is Associated with Increased Erα Levels and Is Repressed by a Dominant Negative Form of Erα

Estrogen receptors (ER), namely ERα and ERβ, are hormone-activated transcription factors with an important role in carcinogenesis. In the present study, we aimed at elucidating the implication of ERα in skin cancer, using chemically-induced mouse skin tumours, as well as cell lines representing dist...

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Main Authors: Logotheti, Stella, Papaevangeliou, Dimitra, Michalopoulos, Ioannis, Sideridou, Maria, Tsimaratou, Katerina, Christodoulou, Ioannis, Pyrillou, Katerina, Gorgoulis, Vassilis, Vlahopoulos, Spiros, Zoumpourlis, Vassilis
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411716/

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