Induction of Paclitaxel Resistance by ERα Mediated Prohibitin Mitochondrial-Nuclear Shuttling

Paclitaxel is a drug within one of the most promising classes of anticancer agents. Unfortunately, clinical success of this drug has been limited by the insurgence of cellular resistance. To address this, Paclitaxel resistance was modeled in an in vitro system using estrogen treated prostate cancer...

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Bibliographic Details
Main Authors: Dong, Pei, Jiang, Lijuan, Liu, Jianye, Wu, Zhiming, Guo, Shengjie, Zhang, Ziling, Zhou, Fangjian, Liu, Zhuowei
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871534/