Anti-Apoptotic Bfl-1 Is the Major Effector in Activation-Induced Human Mast Cell Survival

Mast cells are best known for their role in allergic reactions, where aggregation of FcεRI leads to the release of mast cell mediators causing allergic symptoms. The activation also induces a survival program in the cells, i.e., activation-induced mast cell survival. The aim of the present study was...

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Bibliographic Details
Main Authors: Ekoff, Maria, Lyberg, Katarina, Krajewska, Maryla, Arvidsson, Monica, Rak, Sabina, Reed, John C., Harvima, Ilkka, Nilsson, Gunnar
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376125/