A1/Bfl-1 in leukocyte development and cell death

The function of the anti-apoptotic Bcl-2 family member Bcl2a1/Bfl-1/A1 is poorly understood due to the lack of appropriate loss-of-function mouse models and redundant effects with other Bcl-2 pro-survival proteins upon overexpression. Expression analysis of A1 suggests predominant roles in leukocyte...

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Bibliographic Details
Main Authors: Ottina, Eleonora, Tischner, Denise, Herold, Marco J., Villunger, Andreas
Format: Online
Language:English
Published: Academic Press 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405526/