Conformational Dynamics of Insulin
We have exploited a prandial insulin analog to elucidate the underlying structure and dynamics of insulin as a monomer in solution. A model was provided by insulin lispro (the active component of Humalog®; Eli Lilly and Co.). Whereas NMR-based modeling recapitulated structural relationships of insul...
Main Authors: | Hua, Qing-Xin, Jia, Wenhua, Weiss, Michael A. |
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Format: | Online |
Language: | English |
Published: |
Frontiers Research Foundation
2011
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355934/ |
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