Conformational dynamics of ligand-dependent alternating access in LeuT
The leucine transporter (LeuT) from Aquifex aeolicus is a bacterial homolog of neurotransmitter:sodium symporters (NSS) that catalyze reuptake of neurotransmitters at the synapse. Crystal structures of wild type (WT) and mutants of LeuT have been interpreted as conformational states in the coupled t...
| Main Authors: | , , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050370/ |