Insight into the Stability of Cross-β Amyloid Fibril from VEALYL Short Peptide with Molecular Dynamics Simulation
Amyloid fibrils are found in many fatal neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, type II diabetes, and prion disease. The VEALYL short peptide from insulin has been confirmed to aggregate amyloid-like fibrils. However, the aggregation mechanism of amyloi...
Main Authors: | Ye, Wei, Chen, Yue, Wang, Wei, Yu, Qingfen, Li, Yixue, Zhang, Jian, Chen, Hai-Feng |
---|---|
Format: | Online |
Language: | English |
Published: |
Public Library of Science
2012
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349666/ |
Similar Items
-
Comparisons with Amyloid-β Reveal an Aspartate Residue That Stabilizes Fibrils of the Aortic Amyloid Peptide Medin*
by: Davies, Hannah A., et al.
Published: (2015) -
In vitro fibrillization of Alzheimer’s amyloid-β peptide (1-42)
by: Ann Tiiman, et al.
Published: (2015-09-01) -
β-Amyloid: the key peptide in the pathogenesis of Alzheimer’s disease
by: Sun, Xiaojuan, et al.
Published: (2015) -
Short Peptides as Inhibitors of Amyloid Aggregation
by: Neddenriep, Bradley, et al.
Published: (2011) -
Aβ-40 Y10F Increases βfibrils Formation but Attenuates the Neurotoxicity of Amyloid-β Peptide
by: Dai, Xueling, et al.
Published: (2012)