Metabolism of amyloid β peptide and pathogenesis of Alzheimer’s disease
The conversion of what has been interpreted as “normal brain aging” to Alzheimer’s disease (AD) via transition states, i.e., preclinical AD and mild cognitive impairment, appears to be a continuous process caused primarily by aging-dependent accumulation of amyloid β peptide (Aβ) in the brain. This...
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| Format: | Online |
| Language: | English |
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The Japan Academy
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3758963/ |