PGH1, the Precursor for the Anti-Inflammatory Prostaglandins of the 1-series, Is a Potent Activator of the Pro-Inflammatory Receptor CRTH2/DP2

PGH1, the Precursor for the Anti-Inflammatory Prostaglandins of the 1-series, Is a Potent Activator of the Pro-Inflammatory Receptor CRTH2/DP2

Prostaglandin H1 (PGH1) is the cyclo-oxygenase metabolite of dihomo-γ-linolenic acid (DGLA) and the precursor for the 1-series of prostaglandins which are often viewed as “anti-inflammatory”. Herein we present evidence that PGH1 is a potent activator of the pro-inflammatory PGD2 receptor CRTH2, an a...

Full description

Bibliographic Details
Main Authors: Schröder, Ralf, Xue, Luzheng, Konya, Viktoria, Martini, Lene, Kampitsch, Nora, Whistler, Jennifer L., Ulven, Trond, Heinemann, Akos, Pettipher, Roy, Kostenis, Evi
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307725/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307725/

Similar Items