T cell- but not tumor cell-produced TGF-β1 promotes the development of spontaneous mammary cancer
During their development, tumors acquire multiple capabilities that enable them to proliferate, disseminate and evade immunosurveillance. A putative mechanism is through the production of the cytokine TGF-β1. We showed in our recent studies that T cell-produced TGF-β1 inhibits antitumor T cell respo...
Main Authors: | , , |
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Format: | Online |
Language: | English |
Published: |
Impact Journals LLC
2011
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282091/ |