TGF-β autocrine pathway and MAPK signaling promote cell invasiveness and in vivo mammary adenocarcinoma tumor progression
Breast cancer progression and metastasis have been linked to abnormal signaling by transforming growth factor-β (TGF-β) cytokines. In early-stage breast cancers, TGF-β exhibits tumor suppressor activity by repressing cell proliferation and inducing cell death, whereas in advanced-stage tumors, TGF-β...
| Main Authors: | , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
D.A. Spandidos
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981025/ |