Genome-Wide Analysis to Identify Pathways Affecting Telomere-Initiated Senescence in Budding Yeast
In telomerase-deficient yeast cells, like equivalent mammalian cells, telomeres shorten over many generations until a period of senescence/crisis is reached. After this, a small fraction of cells can escape senescence, principally using recombination-dependent mechanisms. To investigate the pathways...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
Genetics Society of America
2011
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276134/ |