Quantitative Fitness Analysis Identifies exo1∆ and Other Suppressors or Enhancers of Telomere Defects in Schizosaccharomyces pombe

Quantitative Fitness Analysis Identifies exo1∆ and Other Suppressors or Enhancers of Telomere Defects in Schizosaccharomyces pombe

Synthetic genetic array (SGA) has been successfully used to identify genetic interactions in S. cerevisiae and S. pombe. In S. pombe, SGA methods use either cycloheximide (C) or heat shock (HS) to select double mutants before measuring colony size as a surrogate for fitness. Quantitative Fitness Ana...

Full description

Bibliographic Details
Main Authors: Narayanan, Siddharth, Dubarry, Marion, Lawless, Conor, Banks, A. Peter, Wilkinson, Darren J., Whitehall, Simon K., Lydall, David
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500466/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500466/

Similar Items