Quantitative Fitness Analysis Shows That NMD Proteins and Many Other Protein Complexes Suppress or Enhance Distinct Telomere Cap Defects

Quantitative Fitness Analysis Shows That NMD Proteins and Many Other Protein Complexes Suppress or Enhance Distinct Telomere Cap Defects

To better understand telomere biology in budding yeast, we have performed systematic suppressor/enhancer analyses on yeast strains containing a point mutation in the essential telomere capping gene CDC13 (cdc13-1) or containing a null mutation in the DNA damage response and telomere capping gene YKU...

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Bibliographic Details
Main Authors: Addinall, Stephen Gregory, Holstein, Eva-Maria, Lawless, Conor, Yu, Min, Chapman, Kaye, Banks, A. Peter, Ngo, Hien-Ping, Maringele, Laura, Taschuk, Morgan, Young, Alexander, Ciesiolka, Adam, Lister, Allyson Lurena, Wipat, Anil, Wilkinson, Darren James, Lydall, David
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072368/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072368/

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