Monoclonal antibodies and Fc fragments for treating solid tumors

Advances in biotechnology, better understanding of pathophysiological processes, as well as the identification of an increasing number of molecular markers have facilitated the use of monoclonal antibodies and Fc fragments in various fields in medicine. In this context, a rapidly growing number of t...

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Main Authors: Eisenbeis, Andrea M, Grau, Stefan J
Format: Online
Language:English
Published: Dove Medical Press 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266862/
id pubmed-3266862
recordtype oai_dc
spelling pubmed-32668622012-01-30 Monoclonal antibodies and Fc fragments for treating solid tumors Eisenbeis, Andrea M Grau, Stefan J Review Advances in biotechnology, better understanding of pathophysiological processes, as well as the identification of an increasing number of molecular markers have facilitated the use of monoclonal antibodies and Fc fragments in various fields in medicine. In this context, a rapidly growing number of these substances have also emerged in the field of oncology. This review will summarize the currently approved monoclonal antibodies used for the treatment of solid tumors with a focus on their clinical application, biological background, and currently ongoing trials. Dove Medical Press 2012 2012-01-05 /pmc/articles/PMC3266862/ /pubmed/22291463 http://dx.doi.org/10.2147/BTT.S19955 Text en © 2012 Eisenbeis and Grau, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Eisenbeis, Andrea M
Grau, Stefan J
spellingShingle Eisenbeis, Andrea M
Grau, Stefan J
Monoclonal antibodies and Fc fragments for treating solid tumors
author_facet Eisenbeis, Andrea M
Grau, Stefan J
author_sort Eisenbeis, Andrea M
title Monoclonal antibodies and Fc fragments for treating solid tumors
title_short Monoclonal antibodies and Fc fragments for treating solid tumors
title_full Monoclonal antibodies and Fc fragments for treating solid tumors
title_fullStr Monoclonal antibodies and Fc fragments for treating solid tumors
title_full_unstemmed Monoclonal antibodies and Fc fragments for treating solid tumors
title_sort monoclonal antibodies and fc fragments for treating solid tumors
description Advances in biotechnology, better understanding of pathophysiological processes, as well as the identification of an increasing number of molecular markers have facilitated the use of monoclonal antibodies and Fc fragments in various fields in medicine. In this context, a rapidly growing number of these substances have also emerged in the field of oncology. This review will summarize the currently approved monoclonal antibodies used for the treatment of solid tumors with a focus on their clinical application, biological background, and currently ongoing trials.
publisher Dove Medical Press
publishDate 2012
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266862/
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