Monoclonal antibodies and Fc fragments for treating solid tumors
Advances in biotechnology, better understanding of pathophysiological processes, as well as the identification of an increasing number of molecular markers have facilitated the use of monoclonal antibodies and Fc fragments in various fields in medicine. In this context, a rapidly growing number of t...
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2012
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pubmed-32668622012-01-30 Monoclonal antibodies and Fc fragments for treating solid tumors Eisenbeis, Andrea M Grau, Stefan J Review Advances in biotechnology, better understanding of pathophysiological processes, as well as the identification of an increasing number of molecular markers have facilitated the use of monoclonal antibodies and Fc fragments in various fields in medicine. In this context, a rapidly growing number of these substances have also emerged in the field of oncology. This review will summarize the currently approved monoclonal antibodies used for the treatment of solid tumors with a focus on their clinical application, biological background, and currently ongoing trials. Dove Medical Press 2012 2012-01-05 /pmc/articles/PMC3266862/ /pubmed/22291463 http://dx.doi.org/10.2147/BTT.S19955 Text en © 2012 Eisenbeis and Grau, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited. |
repository_type |
Open Access Journal |
institution_category |
Foreign Institution |
institution |
US National Center for Biotechnology Information |
building |
NCBI PubMed |
collection |
Online Access |
language |
English |
format |
Online |
author |
Eisenbeis, Andrea M Grau, Stefan J |
spellingShingle |
Eisenbeis, Andrea M Grau, Stefan J Monoclonal antibodies and Fc fragments for treating solid tumors |
author_facet |
Eisenbeis, Andrea M Grau, Stefan J |
author_sort |
Eisenbeis, Andrea M |
title |
Monoclonal antibodies and Fc fragments for treating solid tumors |
title_short |
Monoclonal antibodies and Fc fragments for treating solid tumors |
title_full |
Monoclonal antibodies and Fc fragments for treating solid tumors |
title_fullStr |
Monoclonal antibodies and Fc fragments for treating solid tumors |
title_full_unstemmed |
Monoclonal antibodies and Fc fragments for treating solid tumors |
title_sort |
monoclonal antibodies and fc fragments for treating solid tumors |
description |
Advances in biotechnology, better understanding of pathophysiological processes, as well as the identification of an increasing number of molecular markers have facilitated the use of monoclonal antibodies and Fc fragments in various fields in medicine. In this context, a rapidly growing number of these substances have also emerged in the field of oncology. This review will summarize the currently approved monoclonal antibodies used for the treatment of solid tumors with a focus on their clinical application, biological background, and currently ongoing trials. |
publisher |
Dove Medical Press |
publishDate |
2012 |
url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266862/ |
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1611502344638300160 |