Microbials for the production of monoclonal antibodies and antibody fragments
•Glycosylated full length antibodies are currently produced in mammalian cells.•Antibody fragments can be produced in microbial organisms.•Strain engineering allows production of full length antibodies in microbials.•Microbials provide several advantages over mammalian cells.
| Main Authors: | , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Elsevier Science Publishers
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906537/ |