Suppression of Cancer Progression by MGAT1 shRNA Knockdown

Suppression of Cancer Progression by MGAT1 shRNA Knockdown

Oncogenic signaling promotes tumor invasion and metastasis, in part, by increasing the expression of tri- and tetra- branched N-glycans. The branched N-glycans bind to galectins forming a multivalent lattice that enhances cell surface residency of growth factor receptors, and focal adhesion turnover...

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Bibliographic Details
Main Authors: Beheshti Zavareh, Reza, Sukhai, Mahadeo A., Hurren, Rose, Gronda, Marcela, Wang, Xiaoming, Simpson, Craig D., Maclean, Neil, Zih, Francis, Ketela, Troy, Swallow, Carol J., Moffat, Jason, Rose, David R., Schachter, Harry, Schimmer, Aaron D., Dennis, James W.
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434202/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434202/

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