Transcriptional Profiling of Human Familial Longevity Indicates a Role for ASF1A and IL7R

Transcriptional Profiling of Human Familial Longevity Indicates a Role for ASF1A and IL7R

The Leiden Longevity Study consists of families that express extended survival across generations, decreased morbidity in middle-age, and beneficial metabolic profiles. To identify which pathways drive this complex phenotype of familial longevity and healthy aging, we performed a genome-wide gene ex...

Full description

Bibliographic Details
Main Authors: Passtoors, Willemijn M., Boer, Judith M., Goeman, Jelle J., van den Akker, Erik B., Deelen, Joris, Zwaan, Bas J., Scarborough, Ann, van der Breggen, Ruud, Vossen, Rolf H. A. M., Houwing-Duistermaat, Jeanine J., van Ommen, Gert Jan B., Westendorp, Rudi G. J., van Heemst, Diana, de Craen, Anton J. M., White, Andrew J., Gunn, David A., Beekman, Marian, Slagboom, P. Eline
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256132/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256132/

Similar Items