Identifying the genomic determinants of aging and longevity in human population studies: Progress and challenges

by Deelen, Joris, Beekman, Marian, Capri, Miriam, Franceschi, Claudio, Slagboom, P Eline
Published 2013

Assessment of the contribution of APOE gene variants to metabolic phenotypes associated with familial longevity at middle age

by Noordam, Raymond, Oudt, Charlotte H., Deelen, Joris, Slagboom, P. Eline, Beekman, Marian, van Heemst, Diana
Published 2016

Genotype-Based Score Test for Association Testing in Families

by Uh, Hae-Won, Beekman, Marian, Meulenbelt, Ingrid, Houwing-Duistermaat, Jeanine J.
Published 2015

Relative validity of the food frequency questionnaire used to assess dietary intake in the Leiden Longevity Study

by Streppel, Martinette T, de Vries, Jeanne HM, Meijboom, Saskia, Beekman, Marian, de Craen, Anton JM, Slagboom, P Eline, Feskens, Edith JM
Published 2013

C-reactive protein and glucose regulation in familial longevity

by Rozing, Maarten P., Mooijaart, Simon P., Beekman, Marian, Wijsman, Carolien A., Maier, Andrea B., Bartke, Andrzej, Westendorp, Rudi G.J., Slagboom, Eline P., van Heemst, Diana
Published 2011

Lipoprotein Particle Profiles Mark Familial and Sporadic Human Longevity

by Heijmans, Bastiaan T, Beekman, Marian, Houwing-Duistermaat, Jeanine J, Cobain, Mark R, Powell, Jonathan, Blauw, Gerard Jan, van der Ouderaa, Frans, Westendorp, Rudi G. J, Slagboom, P. Eline
Published 2006

Lipidomics of familial longevity

by Gonzalez-Covarrubias, Vanessa, Beekman, Marian, Uh, Hae-Won, Dane, Adrie, Troost, Jorne, Paliukhovich, Iryna, Kloet, Frans M, Houwing-Duistermaat, Jeanine, Vreeken, Rob J, Hankemeier, Thomas, Slagboom, Eline P
Published 2013

Fibroblast growth factor 21 reflects liver fat accumulation and dysregulation of signalling pathways in the liver of C57BL/6J mice

by Rusli, Fenni, Deelen, Joris, Andriyani, Evi, Boekschoten, Mark V., Lute, Carolien, van den Akker, Erik B., Müller, Michael, Beekman, Marian, Steegenga, Wilma T
Published 2016

The effect of standardized food intake on the association between BMI and 1H-NMR metabolites

by Schutte, Bianca A. M., van den Akker, Erik B., Deelen, Joris, van de Rest, Ondine, van Heemst, Diana, Feskens, Edith J. M., Beekman, Marian, Slagboom, P. Eline
Published 2016

Classification for Longevity Potential: The Use of Novel Biomarkers

by Beekman, Marian, Uh, Hae-Won, van Heemst, Diana, Wuhrer, Manfred, Ruhaak, L. Renee, Gonzalez-Covarrubias, Vanessa, Hankemeier, Thomas, Houwing-Duistermaat, Jeanine J., Slagboom, P. Eline
Published 2016

Association analysis of insulin-like growth factor-1 axis parameters with survival and functional status in nonagenarians of the Leiden Longevity Study

by van der Spoel, Evie, Rozing, Maarten P., Houwing-Duistermaat, Jeanine J., Slagboom, P. Eline, Beekman, Marian, de Craen, Anton J.M., Westendorp, Rudi G.J., van Heemst, Diana
Published 2015

Copy number variation associates with mortality in long‐lived individuals: a genome‐wide assessment

by Nygaard, Marianne, Debrabant, Birgit, Tan, Qihua, Deelen, Joris, Andersen‐Ranberg, Karen, de Craen, Anton J.M., Beekman, Marian, Jeune, Bernard, Slagboom, Pieternella E., Christensen, Kaare, Christiansen, Lene
Published 2015

How to deal with the early GWAS data when imputing and combining different arrays is necessary

by Uh, Hae-Won, Deelen, Joris, Beekman, Marian, Helmer, Quinta, Rivadeneira, Fernando, Hottenga, Jouke-Jan, Boomsma, Dorret I, Hofman, Albert, Uitterlinden, André G, Slagboom, P E, Böhringer, Stefan, Houwing-Duistermaat, Jeanine J
Published 2012

Homocysteine and Familial Longevity: The Leiden Longevity Study

by Wijsman, Carolien A., van Heemst, Diana, Rozing, Maarten P., Slagboom, P. Eline, Beekman, Marian, de Craen, Anton J. M., Maier, Andrea B., Westendorp, Rudi G. J., Blom, Henk J., Mooijaart, Simon P.
Published 2011

Association between the rs7903146 Polymorphism in the TCF7L2 Gene and Parameters Derived with Continuous Glucose Monitoring in Individuals without Diabetes

by van der Kroef, Sabrina, Noordam, Raymond, Deelen, Joris, Akintola, Abimbola A., Jansen, Steffy W. M., Postmus, Iris, Wijsman, Carolien A., Beekman, Marian, Mooijaart, Simon P., Slagboom, P. Eline, van Heemst, Diana
Published 2016

IL7R gene expression network associates with human healthy ageing

by Passtoors, Willemijn M., van den Akker, Erik B., Deelen, Joris, Maier, Andrea B., van der Breggen, Ruud, Jansen, Rick, Trompet, Stella, van Heemst, Diana, Derhovanessian, Evelyna, Pawelec, Graham, van Ommen, Gert-Jan B., Slagboom, P. Eline, Beekman, Marian
Published 2015

Transcriptional Profiling of Human Familial Longevity Indicates a Role for ASF1A and IL7R

by Passtoors, Willemijn M., Boer, Judith M., Goeman, Jelle J., van den Akker, Erik B., Deelen, Joris, Zwaan, Bas J., Scarborough, Ann, van der Breggen, Ruud, Vossen, Rolf H. A. M., Houwing-Duistermaat, Jeanine J., van Ommen, Gert Jan B., Westendorp, Rudi G. J., van Heemst, Diana, de Craen, Anton J. M., White, Andrew J., Gunn, David A., Beekman, Marian, Slagboom, P. Eline
Published 2012

Correction: Transcriptional Profiling of Human Familial Longevity Indicates a Role for ASF1A and IL7R

by Passtoors, Willemijn M., Boer, Judith M., Goeman, Jelle J., van den Akker, Erik B., Deelen, Joris, Zwaan, Bas J., Scarborough, Ann, van der Breggen, Ruud, Vossen, Rolf H. A. M., Houwing-Duistermaat, Jeanine J., van Ommen, Gert Jan B., Westendorp, Rudi G. J., van Heemst, Diana, de Craen, Anton J. M., White, Andrew J., Gunn, David A., Beekman, Marian, Slagboom, P. Eline
Published 2012

Gene set analysis of GWAS data for human longevity highlights the relevance of the insulin/IGF-1 signaling and telomere maintenance pathways

by Deelen, Joris, Uh, Hae-Won, Monajemi, Ramin, van Heemst, Diana, Thijssen, Peter E., Böhringer, Stefan, van den Akker, Erik B., de Craen, Anton J. M., Rivadeneira, Fernando, Uitterlinden, André G., Westendorp, Rudi G. J., Goeman, Jelle J., Slagboom, P. Eline, Houwing-Duistermaat, Jeanine J., Beekman, Marian
Published 2011

Leukocyte telomere length associates with prospective mortality independent of immune-related parameters and known genetic markers

by Deelen, Joris, Beekman, Marian, Codd, Veryan, Trompet, Stella, Broer, Linda, Hägg, Sara, Fischer, Krista, Thijssen, Peter E, Suchiman, H Eka D, Postmus, Iris, Uitterlinden, André G, Hofman, Albert, de Craen, Anton J M, Metspalu, Andres, Pedersen, Nancy L, van Duijn, Cornelia M, Wouter Jukema, J, Houwing-Duistermaat, Jeanine J, Samani, Nilesh J, Eline Slagboom, P
Published 2014