Association analysis of insulin-like growth factor-1 axis parameters with survival and functional status in nonagenarians of the Leiden Longevity Study

Reduced insulin/insulin-like growth factor 1 (IGF-1) signaling has been associated with longevity in various model organisms. However, the role of insulin/IGF-1 signaling in human survival remains controversial. The aim of this study was to test whether circulating IGF-1 axis parameters associate wi...

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Bibliographic Details
Main Authors: van der Spoel, Evie, Rozing, Maarten P., Houwing-Duistermaat, Jeanine J., Slagboom, P. Eline, Beekman, Marian, de Craen, Anton J.M., Westendorp, Rudi G.J., van Heemst, Diana
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694065/